Radiesse™ is a completely synthetic compound comprised of microspheres of calcium hydroxylapatite in an aqueous gel. Calcium is a natural substance already in the body, so Radiesse causes no allergic reactions making no allergy testing necessary. Radiesse is especially helpful in deeper creases and wrinkles such as the nasolabial folds and corners of the mouth.
Radiesse may last a year or more. The most common side effect, as with any injection, is temporary redness and swelling at the injection site and typically resolves within two to three days.